1256639-47-0

Basic information

• Product Name: (+/-)-7-phenyl-1,6,7,8-tetrahydrocyclopenta[b]pyrazolo[3,4-g]quinoxaline
• CAS NO: 1256639-47-0
• Molecular Weight: 286.336
• Mol File: 1256639-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-7-phenyl-1,6,7,8-tetrahydrocyclopenta[b]pyrazolo[3,4-g]quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-7-phenyl-1,6,7,8-tetrahydrocyclopenta[b]pyrazolo[3,4-g]quinoxaline(1256639-47-0)
• EPA Substance Registry System: (+/-)-7-phenyl-1,6,7,8-tetrahydrocyclopenta[b]pyrazolo[3,4-g]quinoxaline(1256639-47-0)

Safety Data

• Hazardous Substances Data: 1256639-47-0(Hazardous Substances Data)

Upstream product

• 4542-64-7 4-phenylcyclopentane-1,2-dione 
• 7404-68-4 1H-indazole-5,6-diamine 

Relevant articles and documents

Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives

The synthesis of new pyrazolo[3,4-g]quinoxaline derivatives, as well as their Pim kinases (Pim-1, Pim-2, Pim-3) inhibitory potencies and in vitro antiproliferative activities toward a human fibroblast primary culture and three human solid cancer cell lines (PA1, PC3 and DU145) are described. The results obtained in this preliminary structure-activity relationship study have pointed out that most of the compounds in this series exhibited interesting in vitro Pim-3 kinase inhibitory potencies. Moreover, some of the tested compounds have demonstrated favorable antiproliferative potencies.