125700-54-1

Basic information

• Product Name: Acetic acid (R)-2-benzenesulfonyl-3-tert-butoxycarbonylamino-1-methyl-4-(tetrahydro-pyran-2-yloxy)-butyl ester
• CAS NO: 125700-54-1
• Molecular Weight: 485.599
• Mol File: 125700-54-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (R)-2-benzenesulfonyl-3-tert-butoxycarbonylamino-1-methyl-4-(tetrahydro-pyran-2-yloxy)-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (R)-2-benzenesulfonyl-3-tert-butoxycarbonylamino-1-methyl-4-(tetrahydro-pyran-2-yloxy)-butyl ester(125700-54-1)
• EPA Substance Registry System: Acetic acid (R)-2-benzenesulfonyl-3-tert-butoxycarbonylamino-1-methyl-4-(tetrahydro-pyran-2-yloxy)-butyl ester(125700-54-1)

Safety Data

• Hazardous Substances Data: 125700-54-1(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 116611-45-1 (2R)-2-t-butoxycarbonylamino-3-phenylsulfonyl-1-(2-tetrahydropyranyloxy)propane 
• 75-07-0 acetaldehyde 
• 116696-85-6 (2S)-2-t-butoxycarbonylamino-3-phenylsulfonyl-1-(2-tetrahydropyranyloxy)propane 

Downstream Products

• 125700-55-2 [(E)-(R)-2-Benzenesulfonyl-1-(tetrahydro-pyran-2-yloxymethyl)-but-2-enyl]-carbamic acid tert-butyl ester 
• 125700-55-2 [(E)-(S)-2-Benzenesulfonyl-1-(tetrahydro-pyran-2-yloxymethyl)-but-2-enyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

STEREOSELECTIVE SYNTHESIS OF OPTICALLY PURE β,γ-UNSATURATED α-AMINO ACIDS IN BOTH L AND D CONFIGURATIONS

A new method for the stereoselective synthesis of optically pure β,γ-unsaturated α-amino acids in L or D configuration is developed by reacting the dilithiate of (2R)-2-Boc-amino-3-phenylsulfonyl-1-(2-tetrahydropyranyloxy)propane 1 or its (2S)-antipode 2, both derived from L-serine, with aldehyde, followed by stereoselective olefin formation, desulfonylation and oxidation.