1257089-95-4

Basic information

• Product Name: (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)methylamine
• Synonyms: (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)methylamine
• CAS NO: 1257089-95-4
• Molecular Weight: 346.202
• Mol File: 1257089-95-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)methylamine(1257089-95-4)
• EPA Substance Registry System: (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)methylamine(1257089-95-4)

Safety Data

• Hazardous Substances Data: 1257089-95-4(Hazardous Substances Data)

Upstream product

• 1257089-94-3 (6-bromo-quinoxalin-2-yl)(4-fluoro-benzyl)amine 
• 74-88-4 methyl iodide 

Downstream Products

• 1257089-03-4 (4-fluorobenzyl)methyl-[6-(1H-pyrazol-4-yl)quinoxalin-2-yl]amine 

Relevant articles and documents

SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE

The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein X1 is N or N+(O ); X2 is N or CH; Q is a C1-3 alkylene group; R1 is selected from hydrogen, C1-4 hydrocarbyl and hydroxy-C2-4 hydrocarbyl; R2, R3 and R4 are the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Ar1 is an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Ar2 is an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.