125732-50-5

Basic information

• Product Name: 5-Methyl-4-[(2-morpholin-4-yl-cyclohex-2-enyl)-phenyl-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one
• CAS NO: 125732-50-5
• Molecular Weight: 429.562
• Mol File: 125732-50-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Methyl-4-[(2-morpholin-4-yl-cyclohex-2-enyl)-phenyl-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-4-[(2-morpholin-4-yl-cyclohex-2-enyl)-phenyl-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one(125732-50-5)
• EPA Substance Registry System: 5-Methyl-4-[(2-morpholin-4-yl-cyclohex-2-enyl)-phenyl-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one(125732-50-5)

Safety Data

• Hazardous Substances Data: 125732-50-5(Hazardous Substances Data)

Upstream product

• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 130691-00-8 (4E)-4-benzylidene-5-methyl-2-phenyl-3,4-dihydropyrazol-3(3H)-one 

Relevant articles and documents

MICHAEL-TYPE ADDITION REACTIONS OF SOME ENAMINES TO ARYLIDENEPYRAZOLONES

The reaction of the arylidenepyrazolones (1b-d) with 1-morpholinocyclohexene (E2) in refluxing acetonitrile leads to the less substituted alkylated enamines 3b-d.On the other hand, the more substituted alkylated enamines 2a-d are formed when 1a-d react under the same conditions with 1-piperidinocyclohexene (E1).The nature of the enamine in crucial.Nucleophilic attack of the enamine on the α,β-unsaturated carbonyl system of 1 gives rise to a zwitterionic intermediate which through α-proton loss leads to different Michael-type adducts depending on the enamine.