1257405-75-6

Basic information

• Product Name: azidomethyl 4-nitrophenyl carbonate
• Synonyms: azidomethyl 4-nitrophenyl carbonate
• CAS NO: 1257405-75-6
• Molecular Weight: 238.159
• Mol File: 1257405-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: azidomethyl 4-nitrophenyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: azidomethyl 4-nitrophenyl carbonate(1257405-75-6)
• EPA Substance Registry System: azidomethyl 4-nitrophenyl carbonate(1257405-75-6)

Safety Data

• Hazardous Substances Data: 1257405-75-6(Hazardous Substances Data)

Upstream product

• 101623-71-6 iodomethyl(4-nitrophenyl)carbonate 

Downstream Products

• 1257405-76-7 azidomethyl 4-aminobenzylcarbamate 
• 1401429-70-6 3'-[(azidomethyloxycarbonyl)amino]-2',3'-dideoxyguanosine 
• 1401429-74-0 3'-[(azidomethyloxycarbonyl)amino]-2',3'-dideoxythymidine 

Relevant articles and documents

Azidomethyl 4-nitrophenyl carbonate-A reagent for the one-step introduction of the azidomethyloxycarbonyl (Azoc) protecting group

Presented here is the three-step synthesis of azidomethyl 4-nitrophenyl carbonate in 58% overall yield. This carbonate allows for the high-yielding (≥90%) introduction of the phosphine-labile azidomethyloxycarbonyl (Azoc) protecting group in one step. The reagent protects a range of amines, including amino acids. For nonionic substrates, pure carbamates are obtained after extractive workup. Georg Thieme Verlag Stuttgart - New York.