1257983-04-2

Basic information

• Product Name: (E)-3-[2-(4-chlorophenyl)vinyl]-1-methylquinolin-4(1H)-one
• CAS NO: 1257983-04-2
• Molecular Weight: 295.768
• Mol File: 1257983-04-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-[2-(4-chlorophenyl)vinyl]-1-methylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[2-(4-chlorophenyl)vinyl]-1-methylquinolin-4(1H)-one(1257983-04-2)
• EPA Substance Registry System: (E)-3-[2-(4-chlorophenyl)vinyl]-1-methylquinolin-4(1H)-one(1257983-04-2)

Safety Data

• Hazardous Substances Data: 1257983-04-2(Hazardous Substances Data)

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 52166-26-4 1-methyl-3-iodoquinolin-4(1H)-one 
• 38897-99-3 (4-Chlorophenylmethylene)triphenylphosphorane 
• 70027-78-0 1,4-dihydro-1-methyl-4-oxoquinoline-3-carbaldehyde 

Relevant articles and documents

Synthesis of (E)-3-Styrylquinolin-4(1H)-ones in Water by Ohmic Heating: a Comparison with Other Methodologies

Ohmic heating offers a very efficient way to perform organic reactions in aqueous media. Potentially bioactive (E)-3-styrylquinolin-4(1H)-ones were synthesized by the Heck reaction of 3-iodo-1-methylquinolin-4(1H)-one with styrenes in water and with ohmic heating. Pd(OAc)2was used as catalyst, and tetrabutylammonium bromide was used as phase-transfer catalyst in the presence of an inorganic base. Comparison with other established procedures highlight the benefits of this new methodology.