125802-07-5

Basic information

• Product Name: 1-(3-Methoxyphenyl)cyclohexylamine
• Synonyms: 1-(3-Methoxyphenyl)cyclohexylamine;1-(3-Methoxyphenyl)cyclohexanamine
• CAS NO: 125802-07-5
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.3
• Mol File: 125802-07-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-Methoxyphenyl)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methoxyphenyl)cyclohexylamine(125802-07-5)
• EPA Substance Registry System: 1-(3-Methoxyphenyl)cyclohexylamine(125802-07-5)

Safety Data

• Hazardous Substances Data: 125802-07-5(Hazardous Substances Data)

Usage

Chemical structure

1-(3-methoxyphenyl)cyclohexan-1-amine is composed of a cyclohexane ring, an amine group, and a methoxyphenyl group.

Cyclohexane ring

A six-membered carbon ring with each carbon atom bonded to two other carbon atoms and one hydrogen atom.

Amine group

A nitrogen atom bonded to one carbon atom and two hydrogen atoms (-NH2).

Methoxyphenyl group

A benzene ring with a methoxy (CH3O) substituent attached to the 3rd carbon atom.

Potential applications

The compound has potential uses in the pharmaceutical industry and may be of interest in studying various biological processes and reactions.

Medicinal chemistry

Its structure and properties make it a candidate for further research and potential use in medicinal chemistry.

Biological processes

The compound may be involved in or influence various biological processes, making it a subject of interest for researchers.

Chemical reactions

The compound may participate in or catalyze specific chemical reactions, which could be relevant for drug development or understanding biological mechanisms.

Research focus

The compound's unique structure and potential applications make it a valuable subject for further research in the fields of chemistry and biology.

Upstream product

• 706793-32-0 1-(1-azidocyclohexyl)-3-(methyloxy)benzene 
• 1884-42-0 1-(m-Methoxyphenyl)cyclohexanol 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 108-94-1 cyclohexanone 
• 861857-60-5 2-methylpropane-2-sulfinic acid [1-(3-methoxyphenyl)-cyclohexyl]-amide 
• 2398-37-0 3-methoxyphenyl bromide 
• 19924-43-7 3-methoxyphenylacetonitrile 
• 93005-19-7 1-(3-methoxyphenyl)cyclohexanecarbonitrile 
• 111-24-0 1,5-dibromo-pentane 

Downstream Products

• 91164-58-8 N-[1-(3-methoxyphenyl)cyclohexyl]piperidine 
• 79787-43-2 N-[1-(3-hydroxyphenyl)cyclohexyl]piperidine 

Relevant articles and documents

Synthesis method of six-membered ring benzylamine compound

The invention relates to the field of synthesis of organic matters, and particularly discloses a synthesis method of a six-membered ring benzylamine compound, which comprises the following steps: taking a compound D, a compound E and potassium tert-butoxide as raw materials, taking dimethyl sulfoxide as a solvent, reacting at 5-10 DEG C for 1-2 hours, heating to 20 DEG C, reacting, and purifying and separating after the reaction is finished to obtain a compound A; the method comprises the following steps: by taking a compound A, potassium carbonate and hydrogen peroxide as raw materials and dimethyl sulfoxide as a solvent, reacting at 50-65 DEG C, adding ice water to separate out a product after the reaction is finished, filtering and washing to obtain a compound B; dissolving the compound B in acetonitrile, adjusting the pH value to 13-14, adding a saturated sodium hypochlorite solution for reaction, and purifying and washing after the reaction is finished to obtain a compound C; the method has the effect of improving the defect that the synthesis process of the six-membered ring benzylamine compound is not suitable for industrial production.

Synthesis of 4H-1,3-Benzoxazines via Metal- and Oxidizing Reagent-Free Aromatic C-H Oxygenation

An unprecedented electrochemical aromatic C-H oxygenation reaction for the synthesis of 4H-1,3-benzoxazines from easily available N-benzylamides is reported. These oxidative cyclization reactions proceed in a transition metal- and oxidizing reagent-free fashion and produce H2 as only theoretical byproduct. Adapting the C-H oxygenation reaction in an electrochemical microreactor has been demonstrated.

HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention relates to novel hydroxyethylamine compounds of formula (I): (I) having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated-amyloid levels or-amyloid deposits, particularly Alzheimer's disease.