1258538-84-9Relevant articles and documents
Synthesis of 2,4,8-trisubstituted 1,7-naphthyridines by the reaction of 4-(1-aryl-2-methoxyethenyl)-3-isocyanopyridines with excess organolithiums
Kobayashi, Kazuhiro,Kozuki, Taketoshi,Fukamachi, Shuhei,Konishi, Hisatoshi
scheme or table, p. 2086 - 2093 (2010/12/25)
A convenient method for the synthesis of 2,4,8-trisubstituted 1,7-naphthyridines 6 by the reaction of (E)-4-(1-aryl-2-methoxyethenyl)-3- isocyanopyridines 4, which could be easily prepared from commercially available 3-aminopyridine via aroylation of lithium (4-lithiopyridin-3-yl)pivalamide with N-methoxy-N-methylbenzamides, with excess organolithiums has been developed.