1258974-33-2

Basic information

• Product Name: C₂₂H₂₁N₃O₄
• CAS NO: 1258974-33-2
• Molecular Weight: 391.426
• Mol File: 1258974-33-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₁N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₁N₃O₄(1258974-33-2)
• EPA Substance Registry System: C₂₂H₂₁N₃O₄(1258974-33-2)

Safety Data

• Hazardous Substances Data: 1258974-33-2(Hazardous Substances Data)

Upstream product

• 1258974-67-2 C₃₁H₄₁N₃O₄Si 
• 908567-28-2 C₁₁H₁₁BrO₃ 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 17771-33-4 7-hydroxy-2,2-dimethyl-chroman-4-one 
• 1354200-70-6 C₂₉H₃₁F₁₇O₂Si 
• 1354200-50-2 C₁₁H₁₁BrO₂ 
• 1354200-62-6 C₂₇H₂₈BrF₁₇O₂Si 
• 16312-86-0 4-benzyl-1,2,4-triazolidine-3,5-dione 

Relevant articles and documents

Novel benzopyranyl tetracycle compound and pharmaceutical composition having excellent anti-inflammatory effect comprising the same

The present invention relates to a novel compound of chemical formula 3 or 5 and a pharmaceutical composition having an excellent anti-inflammatory effect comprising the same. The compounds inhibit the migration of HMGB1 protein, which is an inflammation-inducing factor, from nucleus to cytoplasm, thereby having an excellent inflammation-inhibiting effect, particularly having an excellent effect of treating or preventing septicemia and the like.COPYRIGHT KIPO 2019

Construction of polyheterocyclic benzopyran library with diverse core skeletons through diversity-oriented synthesis pathway: Part II

As a continuation of our previous report (J. Comb. Chem.2010, 12, 548-558), we accomplished the diversity-oriented synthesis of polyheterocyclic small-molecule library with privileged benzopyran substructure. To ensure the synthetic efficiency, we utilized the solid-phase parallel platform and the fluorous-tag-based solution-phase parallel platform to construct a 284-member polyheterocyclic library with six distinct core skeletons with an average purity of 87% on a scale of 5-10 mg. This library was designed to maximize the skeletal diversity with discrete core skeletons in three-dimensional space and the combinatorial diversity with four different benzopyranyl starting materials and various building blocks. Together with our reported benzopyranyl library, we completed the construction of polyheterocyclic benzopyran library with 11 unique scaffolds and their molecular diversity was visualized in chemical space using principle component analysis (PCA).