1259093-43-0

Basic information

• Product Name: C₁₇H₁₂BrNO₂S
• CAS NO: 1259093-43-0
• Molecular Weight: 374.258
• Mol File: 1259093-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₂BrNO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₂BrNO₂S(1259093-43-0)
• EPA Substance Registry System: C₁₇H₁₂BrNO₂S(1259093-43-0)

Safety Data

• Hazardous Substances Data: 1259093-43-0(Hazardous Substances Data)

Upstream product

• 887587-50-0 methyl 6-bromo-4-chloroquinoline-2-carboxylate 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 1259093-45-2 N-(2-(2-(2-aminoethoxy)ethoxy)-ethyl)-6-bromo-4-(phenylthio)quinoline-2-carboxamide 

Relevant articles and documents

Synthesis of quinoline thioethers as novel small molecule enhancers of monoclonal antibody production in mammalian cell culture

A small library of novel quinoline derivatives containing different thioether substituents at position 4 have been synthesized and screened in murine hybridoma cell culture for their ability to enhance monoclonal antibody (mAb) production. From this set of compounds, four compounds have been discovered that enhanced immunoglobulin G (IgG) titer over negative control cultures due to an increase in specific productivity. These results demonstrate the utility of using organic synthesis and parallel ligand screening methods to discover novel cell culture additives that may be useful for increasing mAb yield in industrial biomanufacturing processes.