125928-19-0

Basic information

• Product Name: C₃₆H₄₈N₄O₁₂
• Synonyms: C₃₆H₄₈N₄O₁₂
• CAS NO: 125928-19-0
• Molecular Weight: 728.797
• Mol File: 125928-19-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₈N₄O₁₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₈N₄O₁₂(125928-19-0)
• EPA Substance Registry System: C₃₆H₄₈N₄O₁₂(125928-19-0)

Safety Data

• Hazardous Substances Data: 125928-19-0(Hazardous Substances Data)

Upstream product

• 118-41-2 Eudesmic acid 
• 4097-89-6 2,2',2''-triaminotriethylamine 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 125928-18-9 (2-Thioxo-thiazolidin-3-yl)-(3,4,5-trimethoxy-phenyl)-methanone 

Relevant articles and documents

Linear and branched alkyl-esters and amides of gallic acid and other (mono-, di- and tri-) hydroxy benzoyl derivatives as promising anti-HCV inhibitors

Linear and branched compounds that contain two, three or five units of galloyl (3,4,5-trihydroxybenzoyl) or its isomer 2,3,4-trihydroxybenzoyl, as well as other mono- or dihydroxybenzoyl moieties have been synthesized. These molecules have been evaluated for their in vitro inhibitory effects against a wide panel of viruses showing preferential activity against HIV and HCV. Our structure-activity relationship studies demonstrated that the 2,3,4-trihydroxybenzoyl moiety provides better antiviral activities than the galloyl (3,4,5-trihydroxybenzoyl) moiety that is present in natural green tea catechins. This observation can be of interest for the further rational exploration of compounds with anti-HCV/HIV properties. The most notable finding with respect to HIV is that the tripodal compounds 43 and 45, with three 2,3,4-trihydroxybenzoyl moieties, showed higher activities than linear compounds with only one or two. With respect to HCV, the linear compounds, 52 and 41, containing a 12 polymethylene chain and two 2,3 di- or 2,3,4 tri-hydroxybenzoyl groups respectively at the ends of the molecule showed good antiviral efficiency. Furthermore, the anti-HCV activity of both compounds was observed at concentrations well below the cytotoxicity threshold. A representative member of these compounds, 41, showed that the anti-HCV activity was largely independent of the genetic make-up of the HCV subgenomic replicon and cell lines used.

Synthesis and characterization of a series of vanadium-tunichrome B 1 analogues. Crystal structure of a tris(catecholamide) complex of vanadium

Two isomeric tris(pyrogallol) derivatives, 2,3,4-TRENPAM and 3,4,5-TRENPAM, have been synthesized with the use of β,β′,β″-triaminotriethylamine (TREN) as the molecular skeleton and the 2,3,4 or 3,4,5 isomers of trihydroxybenzoic acid ligand groups. Vanadi