1259301-22-8Relevant articles and documents
Novel inhibitors of surface layer processing in Clostridium difficile
Tam Dang,Fagan, Robert P.,Fairweather, Neil F.,Tate, Edward W.
, p. 614 - 621 (2012)
Clostridium difficile, a leading cause of hospital-acquired bacterial infection, is coated in a dense surface layer (S-layer) that is thought to provide both physicochemical protection and a scaffold for host-pathogen interactions. The key structural comp
Glycocluster synthesis by native chemical ligation
Wehner, Johannes W.,Lindhorst, Thisbe K.
experimental part, p. 3070 - 3082 (2010/11/05)
Serine-and mannoside-derived thioesters and a mannosidic cysteine derivative were prepared to test native chemical ligation (NCL) for protecting-group-free synthesis of small glycopeptide clusters, which are valuable tools in the glycosciences. The glycopeptides and glycopeptide clusters, respectively, which were obtained via NCL, bear the potential for dimerization and other derivatization of the thiol functionality. Georg Thieme Verlag Stuttgart - New York.