125975-05-5

Basic information

• Product Name: 6-(1-hydroxy-4-pentenyl)-2-cyclohexen-1-one
• CAS NO: 125975-05-5
• Molecular Weight: 180.247
• Mol File: 125975-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(1-hydroxy-4-pentenyl)-2-cyclohexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(1-hydroxy-4-pentenyl)-2-cyclohexen-1-one(125975-05-5)
• EPA Substance Registry System: 6-(1-hydroxy-4-pentenyl)-2-cyclohexen-1-one(125975-05-5)

Safety Data

• Hazardous Substances Data: 125975-05-5(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 2100-17-6 4-pentenal 

Downstream Products

• 129156-16-7 (R*,R*)-(+/-)-2-oxo-γ-<(triethylsilyl)oxy>-3-cyclohexene-1-butanal 
• 129156-17-8 2-oxo-γ-<(triethylsilyl)oxy>cyclohexane-1-butanal 
• 129156-16-7 2-oxo-γ-<(triethylsilyl)oxy>-3-cyclohexene-1-butanal 
• 125975-14-6 6-<1-<(triethylsilyl)oxy>-4-pentenyl>-2-cyclohexen-1-one 

Relevant articles and documents

New Low-Valent Titanium Reagents for Dicarbonyl Coupling and Their Use in a General Method of Annulation

New low-valent titanium reagents have been prepared by reducing TiCl3 (1 mol) with C8K (2 mol) or by reducing TiCl4 (1 mol) with Na-naphthalene (2.75 mol).Ketones carrying a chain that incorporates a suitably placed oxo function (aldehyde or ketone) undergo intramolecular dicarbonyl coupling to produce a bicyclic compound when treated with an excess (16-17 mol of titanium halide per mol of dicarbonyl compound) of one of these reagents.The procedure works well even for highly oxygenated substrates and constitutes a general method of annulation.Other reducing agents besides C8K or Na-naphthalene are suitable, and a brief examination of Na(Hg) and Na-K alloy was made.The C8K/TiCl3 system was also used to convert a cis-1,2-diol into the corresponding olefin.