1260170-07-7Relevant articles and documents
A general catalyst for the β-selective C - H bond arylation of thiophenes with iodoarenes
Ueda, Kirika,Yanagisawa, Shuichi,Yamaguchi, Junichiro,Itami, Kenichiro
supporting information; experimental part, p. 8946 - 8949 (2011/02/21)
Open access: The normally less-reactive β position of thiophenes was previously inaccessible to direct functionalization. However, the β selectivity observed with the catalytic system PdCl2/P{OCH(CF 3)2}3/Ag2CO3 in the arylation of thiophenes with iodoarenes (see scheme) is a remarkably general phenomenon applicable to unsubstituted, monosubstituted, and disubstituted thiophene derivatives, as well as thiophene-containing fused aromatic compounds.