1260236-31-4

Basic information

• Product Name: N-[1-(2,5-dimethylphenyl)vinyl]acetamide
• Synonyms: N-[1-(2,5-dimethylphenyl)vinyl]acetamide
• CAS NO: 1260236-31-4
• Molecular Weight: 189.257
• Mol File: 1260236-31-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-[1-(2,5-dimethylphenyl)vinyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(2,5-dimethylphenyl)vinyl]acetamide(1260236-31-4)
• EPA Substance Registry System: N-[1-(2,5-dimethylphenyl)vinyl]acetamide(1260236-31-4)

Safety Data

• Hazardous Substances Data: 1260236-31-4(Hazardous Substances Data)

Upstream product

• 88166-78-3 1-(2,5-dimethylphenyl)ethanone oxime 
• 108-24-7 acetic anhydride 
• 536-74-3 phenylacetylene 

Downstream Products

• 1392763-61-9 C₁₈H₁₉NO₄ 
• 1604842-42-3 C₁₈H₂₁NO₄ 
• 1532520-71-0 C₂₆H₂₃NO 
• 378215-29-3 2-(2,5-dimethylphenyl)-2-oxoethyl acetate 

Relevant articles and documents

Synthesis of Functionalized Vinylsilanes via Metal-Free Dehydrogenative Silylation of Enamides

A novel method of metal-free dehydrogenative silylation of enamides has been developed. The desired functionalized vinylsilane products were obtained in moderate to good yield and with high stereoselectivities. This protocol displays good tolerance of various functionalities. Furthermore, the high chemoselectivity of this reaction enables us to introduce different unsaturated C-C moieties to the products. The ease of further derivatization of the products to other useful compounds also demonstrates the highly synthetic utility of the current methodology.

Copper-promoted oxidative coupling of enamides and alkynes for the synthesis of substituted pyrroles

An efficient copper-promoted oxidative coupling of enamides with alkynes has been developed for the synthesis of substituted pyrroles. The reaction proceeded through C-H and N-H bond functionalization of enamides under mild conditions.

Coupling of enamides with alkynes or arynes for synthesis of substituted pyridines and isoquinolines via amide activation

A novel and general procedure for Cu-catalyzed coupling of enamides with alkynes to synthesize substituted pyridines was developed. The chemistry was allowed to extend to the synthesis of substituted isoquinolines by coupling of enamides with arynes under transition-metal-free conditions.