1260653-63-1Relevant articles and documents
Microwave-assisted synthesis and antibacterial activity of 1-[3-(3-fluorophenyl) [1,8]naphthyridn-2-yl]-3-(2-oxo-2H-chromenyl)-1H-4- pyrazolecarbaldehydes using solid support
Mogilaiah,Shiva Prasad,Shiva Kumar
experimental part, p. 1417 - 1421 (2011/02/21)
A simple and efficient method for the synthesis of 1-[3-(3- fluorophenyl)[1,8]naphthyridn-2-yl]-3-(2-oxo-2 H -chromenyl)- H - 4-pyrazolecarbaldehydes 4 from 3-[2-(3-(3-fluorophenyl)[1,8]- naphthyridin-2-yl)ethanhydrazonyl]-2 H -2-chromenones (hydra- zones) 3 in the presence of DMF-POCl3 (Vilsmeier-Haack reagent) using silica gel as solid support under microwave irradiation is described. The structural assignments to compounds 3 and 4 are based on their elemental analyses and spectral data. Compounds 4 have been tested for their antibacterial activity.