1260939-66-9 Usage
Description
Terazosin impurity, also known as tert-Butyl 4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate, is a byproduct formed during the synthesis of Terazosin (T105000), an α-1-adrenergic blocker related to prazosin. It is an organic compound with potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
Terazosin impurity is used as a research compound for understanding the synthesis process and the role of impurities in the development of α-1-adrenergic blockers. This knowledge can be applied to improve the synthesis methods and reduce the presence of impurities in the final product, leading to a higher quality and more effective medication.
Used in Quality Control and Analysis:
Terazosin impurity is used as a reference material in quality control and analysis of Terazosin and other related α-1-adrenergic blockers. By comparing the properties and behavior of the impurity with the main compound, researchers and quality control professionals can ensure the purity and efficacy of the final drug product.
Used in Drug Development:
Terazosin impurity can be used as a starting material or intermediate in the development of new drugs with similar mechanisms of action as Terazosin. By studying the structure and properties of the impurity, researchers can gain insights into the design and synthesis of novel α-1-adrenergic blockers with improved pharmacological properties and reduced side effects.
Used in Toxicology Studies:
Terazosin impurity can be used in toxicology studies to evaluate the potential adverse effects of impurities on the safety and efficacy of α-1-adrenergic blockers. This information can be crucial in the development of safer and more effective medications, as well as in the establishment of acceptable impurity limits in the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 1260939-66-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,9,3 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1260939-66:
(9*1)+(8*2)+(7*6)+(6*0)+(5*9)+(4*3)+(3*9)+(2*6)+(1*6)=169
169 % 10 = 9
So 1260939-66-9 is a valid CAS Registry Number.
1260939-66-9Relevant articles and documents
Parallel synthesis of N-arylpiperazines using polymer-assisted reactions
Duncton, Matthew A. J.,Roffey, Jonathan R. A.,Hamlyn, Richard J.,Adams, David R.
, p. 2549 - 2552 (2006)
A series of N-arylpiperazines were prepared in a parallel fashion using palladium-catalyzed cross-coupling, or nucleophilic aromatic displacement chemistries, and polymer-assisted sequestration and purification techniques as key steps.
