1261144-87-9

Basic information

• Product Name: 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
• Synonyms: 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
• CAS NO: 1261144-87-9
• Molecular Weight: 296.369
• Mol File: 1261144-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane(1261144-87-9)
• EPA Substance Registry System: 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane(1261144-87-9)

Safety Data

• Hazardous Substances Data: 1261144-87-9(Hazardous Substances Data)

Upstream product

• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 264608-40-4 8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane 

Relevant articles and documents

C-2 arylation of piperidines through directed transition-metal-catalyzed sp3 C-H activation

All you need is an open vial! The direct α arylation of cyclic alkylamines (see scheme) requires an open vial, as the hydrogen atom involved in the C(sp3)-H-activation process is ultimately released as hydrogen gas. Reports on the formation of hydrogen gas in direct transition-metal- catalyzed functionalizations are still rare. Open-vial reactions proved crucial to this direct arylation procedure as, upon sealing, catalyst deactivation occurs.