1261145-02-1

Basic information

• Product Name: 2,6-bis(3-trifluoromethylphenyl)-1-(pyridin-2-yl)piperidine
• CAS NO: 1261145-02-1
• Molecular Weight: 450.427
• Mol File: 1261145-02-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-bis(3-trifluoromethylphenyl)-1-(pyridin-2-yl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis(3-trifluoromethylphenyl)-1-(pyridin-2-yl)piperidine(1261145-02-1)
• EPA Substance Registry System: 2,6-bis(3-trifluoromethylphenyl)-1-(pyridin-2-yl)piperidine(1261145-02-1)

Safety Data

• Hazardous Substances Data: 1261145-02-1(Hazardous Substances Data)

Upstream product

• 635305-32-7 5,5-dimethyl-2-(3-(trifluoromethyl)phenyl)-1,3,2-dioxaborinane 
• 68654-52-4 2-(piperidin-1-yl)pyridine 

Relevant articles and documents

C-2 arylation of piperidines through directed transition-metal-catalyzed sp3 C-H activation

All you need is an open vial! The direct α arylation of cyclic alkylamines (see scheme) requires an open vial, as the hydrogen atom involved in the C(sp3)-H-activation process is ultimately released as hydrogen gas. Reports on the formation of hydrogen gas in direct transition-metal- catalyzed functionalizations are still rare. Open-vial reactions proved crucial to this direct arylation procedure as, upon sealing, catalyst deactivation occurs.