1261237-70-0Relevant articles and documents
Biaryl modification of the 5′-terminus of one strand of a microRNA duplex induces strand specificity
Ogata, Aya,Furukawa, Chihiro,Sakurai, Kouhei,Iba, Hideo,Kitade, Yukio,Ueno, Yoshihito
supporting information; experimental part, p. 7299 - 7302 (2011/02/22)
MicroRNAs (miRNAs) are single-stranded non-coding RNAs composed of 20-23 nucleotides. They are initially transcribed in the nucleus as pri-miRNAs. After processing, one strand from the miRNA duplex (miR-5p/miR-3p duplex) is loaded onto the RNA-induced sil