126146-36-9Relevant articles and documents
Unsaturated amides derived from 2-amino-3-hydroxycyclopentenone: A Stille approach to the synthesis of asuka-mABA, 2880-II, and limocrocin
Macdonald, Gregor,Alcaraz, Lilian,Wei, Xudong,Lewis, Norman J.,Taylor, Richard J. K.
, p. 9823 - 9836 (2007/10/03)
A Stille palladium catalysed vinyl halide-vinyl stannane or aryl stannane coupling approach to the title compounds is described. The 2- aminocyclopentanedione-derived vinyl bromides (12, n = 1, 2, 3) were prepared and coupled to synthesise 2880-II (4), a Streptomyces metabolite, asuka-mABA (6), obtained during investigations to elucidate the biogenesis of the antibiotic asukamycin, and limocrocin (10), a naturally occurring antibiotic and antiviral agent.
Studies of Precursor-directed Biosynthesis with Streptomyces sp. Part 1. Isolation of Manumycin Analogues by Feeding of Aminobenzoic Acids as C7N Starter Units
Thiericke, Ralf,Zeeck, Axel
, p. 2123 - 2128 (2007/10/02)
Feeding experiments involving variants of the antibiotic manumycin (1) are described.Instead of the (unidentified) natural C7N unit, isomeric aminobenzoic acids were used as alternative biosynthetic starting units.These were fed to Streptomyces parvulus,