1261645-01-5

Basic information

• Product Name: 2-broMo-6-Methoxybenzoyl chloride
• Synonyms: 2-broMo-6-Methoxybenzoyl chloride
• CAS NO: 1261645-01-5
• Molecular Formula: C8H6BrClO2
• Molecular Weight: 249.48904
• Mol File: 1261645-01-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-broMo-6-Methoxybenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-broMo-6-Methoxybenzoyl chloride(1261645-01-5)
• EPA Substance Registry System: 2-broMo-6-Methoxybenzoyl chloride(1261645-01-5)

Safety Data

• Hazardous Substances Data: 1261645-01-5(Hazardous Substances Data)

Usage

Description

2-bromo-6-methoxybenzoyl chloride is an organic chemical compound that serves as an intermediate in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
2-bromo-6-methoxybenzoyl chloride is used as a chemical intermediate for the synthesis of Fluoren-1-ol (F462450), a metabolite of the polycyclic aromatic hydrocarbon (PAH) micropollutant Fluorene (F462002). This metabolite has potential mutagenic effects and is utilized as a biomarker to assess exposure to PAHs and environmental tobacco smoke in the general population.

Upstream product

• 31786-45-5 2-bromo-6-methoxybenzoic acid 

Relevant articles and documents

A general route for 13C-labeled fluorenols and phenanthrenols via palladium-catalyzed cross-coupling and one-carbon homologation

A series of 13C-labeled polyaromatic hydrocarbons (PAHs), fluorenols and phenanthrenols were synthesized from commercially available 13C-labeled starting material giving rise to M + 6 isotopomers. This was accomplished using key pall

HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF

Compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Palladium-catalyzed intramolecular C-H arylation of 2-halo-: N -Boc- N -arylbenzamides for the synthesis of N-H phenanthridinones

A palladium catalyzed synthesis of N-H phenanthridinones was developed via C-H arylation. The protocol gives phenanthridinones regioselectively by one-pot reaction without deprotection. It exhibits broad substrate scope and affords targets in up to 95% yields. Importantly, it could be applied for the less reactive o-chlorobenzamides.