1261648-81-0

Basic information

• Product Name: 1-(5-Bromo-2-iodo-phenyl)-ethanone
• Synonyms: 1-(5-Bromo-2-iodo-phenyl)-ethanone;1-(5-Bromo-2-iodophenyl)ethan-1-one
• CAS NO: 1261648-81-0
• Molecular Formula: C₈H₆BrIO
• Molecular Weight: 324.94111
• Mol File: 1261648-81-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(5-Bromo-2-iodo-phenyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-Bromo-2-iodo-phenyl)-ethanone(1261648-81-0)
• EPA Substance Registry System: 1-(5-Bromo-2-iodo-phenyl)-ethanone(1261648-81-0)

Safety Data

• Hazardous Substances Data: 1261648-81-0(Hazardous Substances Data)

Usage

General Description

1-(5-Bromo-2-iodo-phenyl)-ethanone, also known as 5-bromo-2-iodoacetophenone, is a chemical compound with the molecular formula C8H6BrIO. It is a yellow to brown solid that is often used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. 1-(5-Bromo-2-iodo-phenyl)-ethanone is commonly used in the reagent-mediated synthesis of biologically active molecules and is also used in the preparation of chiral reagents and ligands for asymmetric catalysis. Additionally, 1-(5-Bromo-2-iodo-phenyl)-ethanone has been reported to exhibit potential antimicrobial and antifungal properties, making it of interest for further research in medicinal chemistry and drug discovery.

Upstream product

• 551-93-9 2-aminoacetophenone 
• 29124-56-9 1-(2-amino-5-bromophenyl)ethanone 
• 39263-32-6 2-amino-5-bromobenzonitrile 

Downstream Products

• 1610538-72-1 7-bromo-3-(4-(trifluoromethyl)phenyl)naphthalen-1-ol 
• 1610538-73-2 7-bromo-3-(3-(trifluoromethyl)phenyl)naphthalen-1-ol 
• 1610538-74-3 7-bromo-3-(4-chlorophenyl)naphthalen-1-ol 
• 2039-76-1 1-(phenanthren-3-yl)ethanone 
• 1404432-58-1 4-bromo-1-iodo-2-(prop-1-en-2-yl)benzene 

Relevant articles and documents

COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to a compound having a benzo seven-membered ring structure, and a preparation method therefor, and use thereof. The compound has a structure as represented by formula (I). Provided is use of the compound having the structure and prepared with the preparation method of the present invention, enantiomers, diastereomers, racemates and mixtures thereof of the compound, as well as chemically acceptable salts, crystalline hydrates and solvent mixtures of the compound and the enantiomers, diastereomers, racemates and mixtures thereof of the compound in the preparation of drugs for treating BET Bromodomain BRD4 activity or expression level related diseases.

Domino Synthesis of Thioflavones and Thioflavothiones by Regioselective Ring Opening of Donor-Acceptor Cyclopropane Using In-Situ-Generated Thiolate Anions

A copper-catalyzed intramolecular ring opening of donor-acceptor cyclopropane is developed for the synthesis of 3-alkyl-carbonated thioflavones and further extended to 3-alkyl-carbonated thioflavothione, using xanthate as a sulfur surrogate. This reaction

Palladium-Catalyzed Intermolecular Carbene Insertion Prior to Intramolecular Heck Cyclization: Synthesis of 2-Arylidene-3-aryl-1-indanones

A domino process that converges the migratory insertion of carbene with a Heck reaction has been established as a versatile tool for the synthesis of 2-arylidene-3-aryl-1-indanones from very stable and easily accessible N-tosylhydrazones and 2′-iodochalco