1261816-95-8 Usage
General Description
2-Bromo-3-methoxybenzonitrile is a chemical compound with the molecular formula C8H6BrNO. It is a white to yellow crystalline solid that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-BroMo-3-Methoxybenzonitrile belongs to the class of organic compounds known as benzonitriles, which are aromatic compounds containing a cyano group attached to a benzene ring. 2-Bromo-3-methoxybenzonitrile is primarily used in the production of active pharmaceutical ingredients and is also used as a building block in organic synthesis. It is important to handle this compound with care as it may pose health hazards if mishandled.
Check Digit Verification of cas no
The CAS Registry Mumber 1261816-95-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,8,1 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1261816-95:
(9*1)+(8*2)+(7*6)+(6*1)+(5*8)+(4*1)+(3*6)+(2*9)+(1*5)=158
158 % 10 = 8
So 1261816-95-8 is a valid CAS Registry Number.
1261816-95-8Relevant articles and documents
Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors
Chao, Bo,Tong, Xian-Kun,Tang, Wei,Li, De-Wen,He, Pei-Lan,Garcia, Jean-Michel,Zeng, Li-Min,Gao, An-Hui,Yang, Li,Li, Jia,Nan, Fa-Jun,Jacobs, Michael,Altmeyer, Ralf,Zuo, Jian-Ping,Hu, You-Hong
experimental part, p. 3135 - 3143 (2012/06/01)
The results of a high-throughput screening assay using the DENV-2 replicon showed that the 2,4-diaminoquinazoline derivative 4a has a high dengue virus inhibitory activity (EC50 = 0.15 μM). A series of 2,4-diaminoquinazoline derivatives based on 4a as a lead compound were synthesized and subjected to structure-antidengue activity relationship studies. Among the series of 2,4-diaminoquinazoline derivative probed, 4o was observed to display both the highest antiviral potency (EC50 = 2.8 nM, SI > 1000) and an excellent pharmacokinetic profile.
