126218-06-2

Basic information

• Product Name: L-Aspartic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 4-methyl ester
• CAS NO: 126218-06-2
• Molecular Formula: C24H21NO4
• Molecular Weight: 387.435
• Mol File: 126218-06-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 4-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 4-methyl ester(126218-06-2)
• EPA Substance Registry System: L-Aspartic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 4-methyl ester(126218-06-2)

Safety Data

• Hazardous Substances Data: 126218-06-2(Hazardous Substances Data)

Upstream product

• 2177-62-0 β-methyl L-aspartate 
• 120230-41-3 N-(9-phenylfluoren-9-yl)-L-aspartic acid α-t-butyl β-methyl diester 
• 55135-66-5 9-bromo-9-phenyl-9H-fluorene 

Downstream Products

• 120230-41-3 N-(9-phenylfluoren-9-yl)-L-aspartic acid α-t-butyl β-methyl diester 
• 126218-12-0 α-tert-butyl β-methyl 1-(9-phenylfluoren-9-yl)hexahydroquinolinate 
• 126218-11-9 α-tert-butyl β-methyl 1-(9-phenylfluoren-9-yl)hexahydroquinolinate 
• 126218-09-5 α-tert-butyl β-methyl L-3-(3-chloropropyl)-N-(9-phenylfluoren-9-yl)aspartate 
• 215182-85-7 (2S,5E,8S)-di-tert-butyl 4-oxo-2,8-bis-[N-(9-(9-phenylfluorenyl))amino]non-5-enedioate 
• 215182-78-8 (E)-(S)-5-(9-Phenyl-9H-fluoren-9-ylamino)-hex-2-enedioic acid 6-tert-butyl ester 1-methyl ester 
• 215182-79-9 (S)-2-(9-Phenyl-9H-fluoren-9-ylamino)-hexanedioic acid 1-tert-butyl ester 
• 215182-76-6 tert-butyl (2S)-2-[(9-phenyl-9-fluorenyl)amino]-4-oxobutanoate 
• 215182-75-5 (2S)-tert-butyl 2-[N-(9-(9-phenylfluorenyl))amino]-4-hydroxybutanoate 
• 147698-06-4 1-tert-Butyl 6-methyl (S)-2-[N-(9-phenylfluoren-9-yl)amino]hexandioate 
• 493039-02-4 methyl (3S)-3-[N-(9-phenyl-9-fluorenyl)amino]-4-oxobutanoate 
• 493039-01-3 4-hydroxy-3-(9-phenyl-9H-fluoren-9-ylamino)-butyric acid methyl ester 
• 222619-01-4 N-(9-phenyl-9-fluorenyl)-L-aspartic acid β-methyl ester N-carboxyanhydride 

Relevant articles and documents

Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology

Recent data suggest that the inhibition of arginase (ARG) has therapeutic potential for the treatment of a number of indications ranging from pulmonary and vascular disease to cancer. Thus, high demand exists for selective small molecule ARG inhibitors wi

Selective tert-butyl ester deprotection in the presence of acid labile protecting groups with use of ZnBr2

Chemoselective hydrolysis of tert-butyl esters in the presence of other acid-labile groups has been explored by employing α-amino esters and ZnBr2 in DCM. Although N-Boc and N-trityl groups were found to the labile, PhF protected amines were compatible with these Lewis acid deprotection conditions such that a variety of N-(PhF)amino acids were prepared in good yields from their corresponding tert-butyl esters.

An efficient and practical total synthesis of (+)-vincamine from L-aspartic acid

-