1262285-78-8Relevant articles and documents
Synthesis and spectral characterization of 2-(substituted)-1,3, 2λ5-oxazaphosphinan-2-ones/-2-thiones
Venkateswarlu,Satyanarayana,Rao, C. V. Nageswara,Raju, C. Naga
scheme or table, p. 1273 - 1277 (2011/12/15)
2-(Substituted)-1,3,2λ5-oxazaphosphinan-2-ones/-2-thiones (3-10) were synthesized in a two step process. Condensation of equimolar quantities of 3-aminopropanol (1) with phosphorous oxychloride/thiophosphoryl chloride in dry THF in presence of Et3N to afford the corresponding intermediate 2-chloro-1,3,2λ5-oxazaphosphinan-2-one/-2-thione (2). In the next step 2 reacted in situ with various phenols and aromatic amines in dry THF and TEA to obtain the title compounds. Analytical data, IR, 1H, 13C, 31P and Mass spectral data have been discussed and supported all the structures.