1262333-25-4

Basic information

• Product Name: [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide
• Synonyms: [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide;Meloxicam EP Impurity C;Meloxicam Impurity C(EP)
• CAS NO: 1262333-25-4
• Molecular Formula: C15H15N3O4S2
• Molecular Weight: 365.4273
• Product Categories: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1262333-25-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 540.3±60.0 °C(Predicted)
• Appearance: /
• Density: 1.51±0.1 g/cm3(Predicted)
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide(1262333-25-4)
• EPA Substance Registry System: [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide(1262333-25-4)

Safety Data

• Hazardous Substances Data: 1262333-25-4(Hazardous Substances Data)

Usage

Description

[N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide is a chemical compound that is identified as an impurity in Meloxicam, a preferential cyclooxygenase (COX-2) inhibitor. [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide is characterized by its complex molecular structure, which includes a thiazolylidene group and a benzothiazine-3-carboxamide core, with additional methyl and hydroxy groups.

Uses

Used in Pharmaceutical Industry:
[N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide is used as an impurity in the production of Meloxicam (M216100) for its role as a COX-2 inhibitor. The compound is significant in the pharmaceutical industry due to its association with Meloxicam, which is used to manage pain and inflammation in various conditions such as osteoarthritis and rheumatoid arthritis.
As an impurity, it is essential to monitor and control the levels of [N(Z)]-N-(3,5-DiMethyl-2(3H)-thiazolylidene)-4-hydroxy-2-Methyl-2H-1,2-benzothiazine-3-carboxaMide 1,1-Dioxide in the manufacturing process of Meloxicam to ensure the safety, efficacy, and quality of the final drug product. The presence of impurities can affect the pharmacological activity, stability, and potential side effects of the drug, making it crucial to maintain strict quality control standards.