1262406-62-1

Basic information

• Product Name: C₂₂H₂₃N₃O₅S₃
• CAS NO: 1262406-62-1
• Molecular Weight: 505.64
• Mol File: 1262406-62-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₃N₃O₅S₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₃N₃O₅S₃(1262406-62-1)
• EPA Substance Registry System: C₂₂H₂₃N₃O₅S₃(1262406-62-1)

Safety Data

• Hazardous Substances Data: 1262406-62-1(Hazardous Substances Data)

Upstream product

• 34804-98-3 N-benzyloxycarbonyl-L-alanyl-L-cysteine methyl ester 
• 120-78-5 di(benzothiazol-2-yl)disulfide 
• 149-30-4 2-Mercaptobenzothiazole 

Relevant articles and documents

Detection of protein S-sulfhydration by a tag-switch technique

Protein S-sulfhydration (forming -S-SH adducts from cysteine residues) is a newly defined oxidative posttranslational modification and plays an important role in H2S-mediated signaling pathways. In this study we report the first selective, tag-switch method which can directly label protein S-sulfhydrated residues by forming stable thioether conjugates. Furthermore we demonstrate that H2S alone cannot lead to S-sulfhydration and that the two possible physiological mechanisms include reaction with protein sulfenic acids (P-SOH) or the involvement of metal centers which would facilitate the oxidation of H2S to HS.. Selective detection: The first selective tag-switch method can be used to directly label protein persulfide units (sites of S-sulfhydration) in the form of stable thioether conjugates. It is thought that H2S alone cannot lead to S-sulfhydration and that the two possible physiological mechanisms include reaction with protein sulfenic acids (P-SOH) and the involvement of metal centers, which would facilitate the oxidation of H2S to HS..