1262536-09-3

Basic information

• Product Name: C₆₁H₁₁₈N₂O₁₃Si₃
• Synonyms: C₆₁H₁₁₈N₂O₁₃Si₃
• CAS NO: 1262536-09-3
• Molecular Weight: 1171.87
• Mol File: 1262536-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₁H₁₁₈N₂O₁₃Si₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₁H₁₁₈N₂O₁₃Si₃(1262536-09-3)
• EPA Substance Registry System: C₆₁H₁₁₈N₂O₁₃Si₃(1262536-09-3)

Safety Data

• Hazardous Substances Data: 1262536-09-3(Hazardous Substances Data)

Upstream product

• 63864-45-9 (9S)-9-dihydroerythromycin A 
• 58577-87-0 O-benzyl-L-serinol 
• 4726-96-9 O-Benzyl-L-serine 
• 994-30-9 triethylsilyl chloride 
• 1262535-97-6 C₅₅H₁₀₉NO₁₃Si₃ 
• 497832-22-1 (9S)-9,2',4''-O-tris(triethylsilyl)-9-dihydroerythromycin A 

Downstream Products

• 1262536-14-0 C₆₁H₁₁₆N₂O₁₂Si₃ 
• 1262536-18-4 C₄₃H₇₄N₂O₁₂ 

Relevant articles and documents

Synthesis and antibacterial activity of a novel class of 15-membered macrolide antibiotics, "11a-Azalides"

An efficient method for the reconstruction of the 9-dihydroerythromycin A macrolactone skeleton has been established. The key steps are oxidative cleavage at the 11,12-position and reconstruction after insertion of an appropriate functionalized amino alcohol. Novel 15-membered macrolides, we named as "11a-azalides", were synthesized based on the above methodology and evaluated for their antibacterial activity. Among them, (13R)-benzyloxymethyl- 11a-azalide showed the most potent Streptococcus pneumoniae activity, with improved activity against a representative erythromycin-resistant strain compared to clarithromycin (CAM).