126260-67-1

Basic information

• Product Name: 6-hydroxy-1-trifluoromethyl-1,2,3,4-tetrahydro- 9H-pyridoindole
• Synonyms: 6-hydroxy-1-trifluoromethyl-1,2,3,4-tetrahydro- 9H-pyridoindole
• CAS NO: 126260-67-1
• Molecular Formula: C12H11F3N2O
• Molecular Weight: 256.22
• Mol File: 126260-67-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-hydroxy-1-trifluoromethyl-1,2,3,4-tetrahydro- 9H-pyridoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-1-trifluoromethyl-1,2,3,4-tetrahydro- 9H-pyridoindole(126260-67-1)
• EPA Substance Registry System: 6-hydroxy-1-trifluoromethyl-1,2,3,4-tetrahydro- 9H-pyridoindole(126260-67-1)

Safety Data

• Hazardous Substances Data: 126260-67-1(Hazardous Substances Data)

Upstream product

• 50-67-9 3-(2-aminoethyl)-1H-indol-5-ol 
• 433-27-2 ethyl trifluoroacetaldehyde hemiacetal 

Relevant articles and documents

SYNTHESIS OF 1-TRIFLUOROMETHYL-β-CARBOLINE DERIVATIVES

Benzene-ring substituted 1-trifluoromethyl-β-carbolines (IV) were synthesized in 23-27percent overall yield by selenium dioxide dehydrogenation of the corresponding 1-trifluoromethyl-1,2,3,4-tetrahydro-β-carbolines(II); the latter compounds were obtained in high yield by Mannich-type condensation of the respective tryptamines with trifluoroacetaldehyde.Partial dehydrogenation of II with potassium permanganate provided 1-trifluoromethyl-3,4-dihydro-β-carbolines (III).L-tryptophan gave, following condensation, esterification and dehydrogenation, 3-carboethoxy-1-trifluoromethyl-β-carboline (IVf) in 84.8percent overall yield.The halogenation and nitration of 1-trifluoromethyl-β-carboline (IVa) were also examined.