1262803-64-4

Basic information

• Product Name: methyl 5-(hydroxymethyl)pyrazine-2-carboxylate
• Synonyms: methyl 5-(hydroxymethyl)pyrazine-2-carboxylate
• CAS NO: 1262803-64-4
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168
• Mol File: 1262803-64-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 5-(hydroxymethyl)pyrazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(hydroxymethyl)pyrazine-2-carboxylate(1262803-64-4)
• EPA Substance Registry System: methyl 5-(hydroxymethyl)pyrazine-2-carboxylate(1262803-64-4)

Safety Data

• Hazardous Substances Data: 1262803-64-4(Hazardous Substances Data)

Usage

General Description

Methyl 5-(hydroxymethyl)pyrazine-2-carboxylate is a chemical compound with the molecular formula C8H10N2O3. It is a derivative of pyrazine, a heterocyclic organic compound. methyl 5-(hydroxymethyl)pyrazine-2-carboxylate is used in various industries, including the food and pharmaceutical sectors, for its distinctive and desirable aroma and flavor attributes. It is commonly used as a flavoring ingredient in food products, particularly in savory and meaty applications. Additionally, it has potential applications in the pharmaceutical industry for its aromatic properties and potential medicinal uses. However, like all chemical compounds, it should be handled and used with care and in accordance with safety regulations.

Upstream product

• 710322-57-9 5-formylpyrazine-2-carboxylic acid methyl ester 
• 210037-58-4 5-bromopyrazine-2-carboxylic acid methyl ester 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 13051-89-3 dimethyl Pyrazine-2,5-dicarboxylate 
• 122-05-4 2,5-pyrazinedicarboxylic acid 

Downstream Products

• 1388149-44-7 N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-(fluoromethyl)-pyrazine-2-carboxamide 
• 1388149-45-8 C₂₄H₂₄F₅N₅O₄S 
• 193966-70-0 methyl 5-(bromomethyl)pyrazine-2-carboxylate 

Relevant articles and documents

DRUG TARGETING CANCER STEM CELL

The present invention provides an anti-tumor agent comprising a compound of formula (1) or a pharmaceutically acceptable salt thereof, wherein ring Q1 is optionally-substituted C6-10 aryl, etc.; R1 and R2 are independently hydrogen atom, etc.; W1 is C1-4 alkylene which may be optionally substituted with 1 to 3 fluorine atoms or C3-7 cycloalkyl; W2 is -NR4aC(O)-, etc. wherein R4a is hydrogen atom or C1-6 alkyl; ring Q2 is optionally-substituted C6-10 aryl, etc., in combination with at least one agent selected from the group consisting of an anti-cancer agent, an anti-diabetic agent, an agent for treating dyslipidemia, an agent for treating multiple sclerosis, a steroidal anti-inflammatory agent, a non-steroidal anti-inflammatory agent, an anti-fungal agent, and a pharmaceutically acceptable salt thereof.

PIPERIDINE DERIVATIVES FOR GPR119 AGONIST

The present invention relates to novel piperidine derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel piperidine derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.

FUSED AMINODIHYDROTHIAZINE DERIVATIVES USEFUL AS BACE INHIBITORS

The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; A is CH or N; Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or -C≡N; and pharmaceutically acceptable salts thereof; which compound has an Αβ production inhibitory effect or a BACEl inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Αβ and typified by Alzheimer-type dementia.