126301-23-3

Basic information

• Product Name: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride
• Synonyms: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride
• CAS NO: 126301-23-3
• Molecular Weight: 265.761
• Mol File: 126301-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride(126301-23-3)
• EPA Substance Registry System: (S)-2-amino-3-phenylpropyl methanesulphonate hydrochloride(126301-23-3)

Safety Data

• Hazardous Substances Data: 126301-23-3(Hazardous Substances Data)

Upstream product

• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 126301-19-7 (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate 

Downstream Products

• 126301-32-4 (S)-2-amino-3-phenylpropane-1-sulfonic acid 

Relevant articles and documents

Syntheses and Properties of Optically Active 2-Substituted Taurines

The synthesis of nine 2-substituted taurines (5a-i), including the marine natural product D-cysteinolic acid (5f), are described.These involve the successive conversion of N-t-butoxycarbonyl(Boc)-protected amino acid esters (1) into the N-Boc-2-aminoethanols (2), their O-mesylated derivatives (3), the deprotected 2-aminoethyl methanesulphonates (4), followed by the replacement of the mesyloxy group by a sulpho group to give the optically active taurines (5a-e,g-i).Hydrogenolysis of 2-benzyloxymethyltaurine (5e) gives D-cysteinolic acid (5f).The structure of another of the products, (5b), is also confirmed by an alternative synthesis from N-Boc-valine methyl ester (1b) via twoβ-bromoethylamine derivatives, (6b) and (7b).