126474-11-1

Basic information

• Product Name: 2-(1-Phenyl-4-trimethylsilanyl-but-3-ynyloxymethyl)-pyrazine
• CAS NO: 126474-11-1
• Molecular Weight: 310.471
• Mol File: 126474-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(1-Phenyl-4-trimethylsilanyl-but-3-ynyloxymethyl)-pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Phenyl-4-trimethylsilanyl-but-3-ynyloxymethyl)-pyrazine(126474-11-1)
• EPA Substance Registry System: 2-(1-Phenyl-4-trimethylsilanyl-but-3-ynyloxymethyl)-pyrazine(126474-11-1)

Safety Data

• Hazardous Substances Data: 126474-11-1(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 126473-96-9 (1-phenyl-3-butynyloxy)methylpyrazine 
• 39204-47-2 2-(chloromethyl)pyrazine 
• 1743-36-8 1-phenylbut-3-yn-1-ol 

Downstream Products

• 126474-19-9 3-Phenyl-5-trimethylsilanyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine 
• 126474-18-8 6-Phenyl-4-trimethylsilanyl-5,8-dihydro-6H-pyrano[3,4-b]pyridine 

Relevant articles and documents

INTRAMOLECULAR INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF PYRAZINES

Thermally induced intramolecular Diels-Alder cyclisations of (alkynyloxyalkyl)pyrazines to dihydropyranopyridines have been studied in the solvent undecane.The introduction of a phenyl group in the α-position of the 3-butynyloxymethyl side chain leads to a 3-4 fold increase of the reaction rate, while the influence of a γ-phenyl group on the rate is negligible.The (3-butynyloxymethyl)pyrazine reacts about 7 times slower than the (3-propynyloxyethyl)pyrazine; the presence of a trimethylsilyl group at the terminus of the alkyne decreases in general the rate of the intramolecular cyclisation.The mechanisms are discussed.