1265015-19-7

Basic information

• Product Name: (E)-3-(4-tert-butylphenyl)acrylic acid n-butyl ester
• Synonyms: (E)-3-(4-tert-butylphenyl)acrylic acid n-butyl ester
• CAS NO: 1265015-19-7
• Molecular Weight: 260.376
• Mol File: 1265015-19-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-tert-butylphenyl)acrylic acid n-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-tert-butylphenyl)acrylic acid n-butyl ester(1265015-19-7)
• EPA Substance Registry System: (E)-3-(4-tert-butylphenyl)acrylic acid n-butyl ester(1265015-19-7)

Safety Data

• Hazardous Substances Data: 1265015-19-7(Hazardous Substances Data)

Upstream product

• 15084-51-2 4-tert-butylbenzenesulfonyl chloride 
• 141-32-2 acrylic acid n-butyl ester 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 27798-45-4 1-allyl-4-(tert-butyl)benzene 
• 71-36-3 butan-1-ol 
• 63488-10-8 4-tert-butylmagnesium bromide 

Relevant articles and documents

Palladium-catalyzed aerobic oxidative double allylic C-H oxygenation of alkenes: A novel and straightforward route to α,β-unsaturated esters

A mild tandem oxidative functionalization of allyl aromatic hydrocarbons was accomplished using the catalytic system of Pd(OAc)2/DMA under 1 atm O2. The green twofold C-O bond formation involving double allylic C-H oxygenation unlocks opportunities for markedly different synthetic strategies. Moreover, the reaction affords aryl α,β-unsaturated esters directly from readily available terminal olefins in moderate to good yields with excellent chemo- and stereoselectivities.

Oxygen-promoted coupling of arylboronic acids with olefins catalyzed by [CA]2[PdX4] complexes without a base

Abstract An efficient method was developed for the oxidative Heck reaction between arylboronic acids and olefins catalyzed by anionic palladium complexes of the type [CA]x[PdCl4] (x = 1,2) and [CA]2[Pd2Cl6] (CA = imidazolium or pyridinium cation). Molecular oxygen was employed as an environmentally benign oxidant to regenerate Pd(II) species during the reaction. The elaborated protocol could be applied to the coupling of different arylboronic acids with both electron-rich and electron-poor olefins. The catalyst system was further employed for the one-pot oxidative Heck reaction followed by the Heck coupling to build conjugated compounds in good yield. Mass spectrometry (ESI-MS) and UV-vis spectroscopy was used to identify palladium-containing complexes in the reactions. A plausible reaction mechanism of the oxidative Heck reaction was proposed.

Pd-catalyzed desulfitative Heck coupling with dioxygen as the terminal oxidant

A Pd-catalyzed desulfitative Heck-type reaction of aromatic sulfinic acid sodium salts with various olefins is developed with O2 as the terminal oxidant under mild conditions. The presence of phosphane ligand DPEphos in anisole can significantly enhance the reaction selectivity.