1265359-42-9Relevant articles and documents
Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)
Li, Xianfeng,Hernandez, Vincent,Rock, Fernando L.,Choi, Wai,Mak, Yvonne S. L.,Mohan, Manisha,Mao, Weimin,Zhou, Yasheen,Easom, Eric E.,Plattner, Jacob J.,Zou, Wuxin,Pérez-Herrán, Esther,Giordano, Ilaria,Mendoza-Losana, Alfonso,Alemparte, Carlos,Rullas, Joaquín,Angulo-Barturen, I?igo,Crouch, Sabrinia,Ortega, Fátima,Barros, David,Alley
, p. 8011 - 8026 (2017/10/18)
There is an urgent need to develop new and safer antitubercular agents that possess a novel mode of action. We synthesized and evaluated a novel series of 3-aminomethyl 4-halogen benzoxaboroles as Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (L
TRISUBSTITUTED BORON-CONTAINING MOLECULES
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, (2011/02/24)
This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.