1266084-51-8 Usage
General Description
Acoziborole is a chemical compound which acts as a potent and selective inhibitor of trypanosomal protein translation. This makes it a promising candidate for the treatment of trypanosomiasis, a parasitic disease caused by the Trypanosoma brucei parasite. Acoziborole works by targeting and inhibiting the enzyme trypanosomal alternative oxidase, leading to the disruption of the parasite's energy metabolism and ultimately causing its death. Studies have shown that acoziborole has low toxicity in humans and has demonstrated significant efficacy in preclinical trials, making it a potentially valuable tool in the fight against trypanosomiasis, a disease that primarily affects people in sub-Saharan Africa.
Check Digit Verification of cas no
The CAS Registry Mumber 1266084-51-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,6,0,8 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1266084-51:
(9*1)+(8*2)+(7*6)+(6*6)+(5*0)+(4*8)+(3*4)+(2*5)+(1*1)=158
158 % 10 = 8
So 1266084-51-8 is a valid CAS Registry Number.
1266084-51-8Relevant articles and documents
BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS
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, (2011/02/24)
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective
