126727-04-6

Basic information

• Product Name: 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID
• Synonyms: N-FMOC-DL-phenylalanine;N-9-Fluorenylmethoxycarbonyl-DL-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl DL-Phe-OH
• CAS NO: 126727-04-6
• Molecular Formula: C₂₄H₂₁NO₄
• Molecular Weight: 387.43
• Mol File: 126727-04-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID(126727-04-6)
• EPA Substance Registry System: 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID(126727-04-6)

Safety Data

• Hazardous Substances Data: 126727-04-6(Hazardous Substances Data)

Usage

General Description

2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid is a chemical compound with a long name that describes its structure. It is a derivative of propionic acid, a carboxylic acid, and it also contains a fluorenyl group and a phenyl group. 2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-PHENYL-PROPIONIC ACID is commonly used in pharmaceutical research and drug development due to its potential therapeutic properties. It may have anti-inflammatory or analgesic effects, making it a possible candidate for the development of new medications for pain relief and treatment of inflammatory conditions. Its specific chemical structure and properties make it a valuable target for further studies and potential drug design.

Upstream product

• 909114-66-5 9-fluorenylmethyl 4,6-dimethoxy-1,3,5-triazinyl carbonate 
• 150-30-1 Phenylalanine 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 79396-87-5 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 2,4,5-trichloro-phenyl ester 
• 79396-87-5 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 2,4,5-trichloro-phenyl ester 

Relevant articles and documents

Determination of Chemical and Enantiomeric Purity of α-Amino Acids and their Methyl Esters as N-Fluorenylmethoxycarbonyl Derivatives Using Amylose-derived Chiral Stationary Phases

Liquid chromatographic enantiomer separation and simultaneous determination of chemical and enantiomeric purity of α-amino acids and their methyl esters as N-fluorenylmethoxycarbonyl (FMOC) derivatives was performed on three covalently bonded type chiral stationary phases (CSPs) derived from amylose derivatives. The enantiomer separation of α-amino acid esters as N-FMOC derivatives was better than that of the corresponding acids, especially for CSP 1 and 2. Chemical impurities as the corresponding racemic acids present in several commercially available racemic amino acid methyl esters were observed to be 0.49–17.50%. Enantiomeric impurities of several commercially available L-amino acid methyl esters were found to be 0.03–0.58%, whereas chemical impurities as the corresponding racemic acids present in the same analytes were found to be 0.13–13.62%. This developed analytical method will be useful for the determination of chemical and enantiomeric purity of α-amino acids and/or esters as N-FMOC derivatives using amylose-derived CSPs.

Rapid and sensitive LC-MS approach to quantify non-radioactive transition metal impurities in metal radionuclides

A rapid and sensitive LC-MS approach for the quantification of non-radioactive metal contaminants present in metal radionuclide formulations was developed. Traditional 12C/1H and heavy stable isotope 13C/2H-labeled chelator-amino acid conjugates are used as chelating agents to quantify contaminating transition metals, allowing for determination of effective specific activity of radio-metals. The Royal Society of Chemistry 2013.

Facile and selective deallylations of esters under 'aqueous' free-radical conditions

The conversion of allyl esters into carboxylic acids using radical initiators has been achieved in high yields in aqueous media. Georg Thieme Verlag Stuttgart.