126759-33-9

Basic information

• Product Name: Benzoic acid, 3-ethenyl-4-nitro-, methyl ester
• CAS NO: 126759-33-9
• Molecular Formula: C10H9NO4
• Molecular Weight: 207.186
• Mol File: 126759-33-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-ethenyl-4-nitro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-ethenyl-4-nitro-, methyl ester(126759-33-9)
• EPA Substance Registry System: Benzoic acid, 3-ethenyl-4-nitro-, methyl ester(126759-33-9)

Safety Data

• Hazardous Substances Data: 126759-33-9(Hazardous Substances Data)

Upstream product

• 74-85-1 ethene 
• 126759-30-6 3-bromo-4-nitrobenzoate methyl ester 
• 88071-90-3 3-bromomethyl-4-nitro-benzoic acid methyl ester 
• 24078-21-5 methyl 3-methyl-4-nitrobenzoate 
• 50-00-0 formaldehyd 

Downstream Products

• 1011-65-0 5-methoxycarbonylindole 
• 110073-67-1 methyl 4-amino-3-ethenylbenzoate 
• 126759-41-9 2-<(5-methoxycarbonyl-2-nitrophenyl)methyl>-1,3-dioxane 

Relevant articles and documents

Palladium-Catalyzed Synthesis of Indoles by Reductive N-Heteroannulation of 2-Nitrostyrenes

A palladium-phosphine catalyzed reductive N-heteroannulation of 2-nitrostyrenes, in the presence of carbon monoxide, producing indoles has been developed. Indoles were obtained, in moderate to excellent yield, from substituted 2-nitrostyrenes having either electron-withdrawing (NO2 and CO2-Me) or electron-donating (Br, OH, Me, OMe, and OTf) substituents on the aromatic ring. Best results were obtained using palladium diacetate (6 mol percent) together with triphenylphosphine (24 mol percent) as the catalytic system, under 4 atm of carbon monoxide in acetonitrile at 70 °C. Other palladium(II) and palladium(0) complexes also catalyze the reaction.