126790-21-4Relevant articles and documents
Inhibiting Aβ toxicity in Alzheimer's disease by a pyridine amine derivative
Zhu, Zhenzhu,Yang, Tao,Zhang, Lei,Liu, Lulu,Yin, Enmao,Zhang, Changli,Guo, Zijian,Xu, Chen,Wang, Xiaoyong
, p. 330 - 339 (2019)
Alzheimer's disease (AD) is a neurodegenerative disorder with no radical therapy. Aggregation of amyloid β-peptide (Aβ) induced by various factors is associated with pathogenesis of AD. A pyridine amine derivative, 3-bis(pyridin-2-ylmethyl)aminomethyl-5-h
An efficient method for the preparation of benzylic bromides
Liu,Chen,Deng,Tu
, p. 2078 - 2080 (2001)
Substituted benzylic compounds are brominated with an excess of N-bromosuccinimide (NBS) in CCl4 to the corresponding polybrominated mixtures which are then debrominated with diethyl phosphite and N,N-diisopropylethylamine to afford the desired monobromides in satisfactory yields and high purity.