126812-00-8

Basic information

• Product Name: 2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-3-(2-oxo-tetrahydro-furan-3-yl)-propionic acid ethyl ester
• Synonyms: 2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-3-(2-oxo-tetrahydro-furan-3-yl)-propionic acid ethyl ester
• CAS NO: 126812-00-8
• Molecular Weight: 344.411
• Mol File: 126812-00-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-3-(2-oxo-tetrahydro-furan-3-yl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-3-(2-oxo-tetrahydro-furan-3-yl)-propionic acid ethyl ester(126812-00-8)
• EPA Substance Registry System: 2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-3-(2-oxo-tetrahydro-furan-3-yl)-propionic acid ethyl ester(126812-00-8)

Safety Data

• Hazardous Substances Data: 126812-00-8(Hazardous Substances Data)

Upstream product

• 547-65-9 α-methylene-γ-butyrolactone 
• 95271-74-2 1-benzyl-2-ethoxycarbonylmethyleneimidazolidine 

Downstream Products

• 936-83-4 2-Oxo-3-<2-carboxy-ethyl>-tetrahydrofuran 
• 126812-10-0 3-[2-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-ethyl]-dihydro-furan-2-one 

Relevant articles and documents

CONJUGATE ADDITION OF IMIDAZOLINES:A PROTOCOL FOR 1,4-ADDITION TO ENONES AND OTHER ACCEPTORS

The enaminoester 1-benzyl-2-ethoxycarbonylmethyleneimidazolidine reacts with α,β-enones and other Michael acceptors to give 1,4-adducts; removal of the ethoxycarbonyl group completes overall conjugate addition of the imidazoline α-anion (which itself adds 1,2 to enones),and hydrolysis affords carboxylic acids.