1268444-44-5

Basic information

• Product Name: (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)glycinate
• Synonyms: (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)glycinate
• CAS NO: 1268444-44-5
• Molecular Weight: 391.599
• Mol File: 1268444-44-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)glycinate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)glycinate(1268444-44-5)
• EPA Substance Registry System: (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)glycinate(1268444-44-5)

Safety Data

• Hazardous Substances Data: 1268444-44-5(Hazardous Substances Data)

Upstream product

• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 
• 106-93-4 ethylene dibromide 
• 65253-04-5 (-)-8-phenylmenthol 

Downstream Products

• 1268444-62-7 (-)-8-phenylmenthyl N-(1,3-dithiolan-2-ylidene)-α-(2-chloro-4-nitrophenyl)glycinate 

Relevant articles and documents

Synthesis of nitroaryl derivatives of glycine via oxidative nucleophilic substitution of hydrogen in nitroarenes

Carbanion of ethyl N-(1,3-dithiolan-2-ylidene)glycinate adds to activated nitroarenes mostly in para position to the nitro group. Subsequent oxidation of the resulting σH adducts with DDQ gave respective α-nitroarylated glycine derivatives in moderate yields. The reaction of esters of chiral alcohols such as (-)-menthol or (-)-8-phenylmenthol proceeds with a moderate or high diastereoselectivity leading to enantiomerically enriched nitroarylglycines. ARKAT-USA, Inc.