1268872-88-3

Basic information

• Product Name: (2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole
• CAS NO: 1268872-88-3
• Molecular Weight: 394.56
• Mol File: 1268872-88-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole(1268872-88-3)
• EPA Substance Registry System: (2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole(1268872-88-3)

Safety Data

• Hazardous Substances Data: 1268872-88-3(Hazardous Substances Data)

Upstream product

• 425615-42-5 (R,R)-1,2-bis(2,4,6-trimethylphenyl)-1,2-ethanediamine 
• 643-79-8 o-phthalic dicarboxaldehyde 

Relevant articles and documents

The reaction of aromatic dialdehydes with enantiopure 1,2-diamines: An expeditious route to enantiopure tricyclic amidines

The condensation of enantiopure 1,2-diamines with terephthalaldehyde, isophthalaldehyde or 2-iodo-, 2-alkyl- or 2-aryl-1,3-benzenedialdehydes in toluene followed by treatment with NBS in dichloromethane gives direct access to enantiopure 1,4-, and 1,3-di(4,5-dihydro-1H-imidazol-2-yl)benzenes (diamidines). The condensation of o-phthalaldehyde, and other ortho-disubstituted aromatic dialdehydes, with enantiopure 1,2-diamines, without NBS, gives enantiopure 3,5-dihydro-2H-imidazol-[2,1]-isoindoles.