126922-09-6

Basic information

• Product Name: ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate
• Synonyms: ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate
• CAS NO: 126922-09-6
• Molecular Weight: 322.364
• Mol File: 126922-09-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate(126922-09-6)
• EPA Substance Registry System: ethyl 2-(4-cyano-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yloxy)acetate(126922-09-6)

Safety Data

• Hazardous Substances Data: 126922-09-6(Hazardous Substances Data)

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 5407-83-0 ethyl 2-cyano-2-cyclopentylideneacetate 
• 126921-96-8 3-oxo-1-phenyl-3,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-4-carbonitrile 
• 100-52-7 benzaldehyde 
• 875-61-6 Cyanocarbamidomethylenecyclopentane 

Downstream Products

• 126922-05-2 7<6-cyano-2-phenyl-cyclopenta pyridyl> oxyacetohydrazide 
• 488843-85-2 5-phenyl-3,6,7,8-tetrahydrocyclopenta[d]pyrazolo[3,4-b]pyridin-1-amine 

Relevant articles and documents

Synthesis and structure of condensed triazolo- and tetrazolopyrimidines

Herein we present the synthesis of several new hydrazino derivatives of cyclopenta[c]pyridine, 5,6,7,8-tetrahydroisoquinoline and pyrano[3,4-c]pyridine from 3-oxo-4-cyano fused pyridine derivatives. The hydrazino derivatives obtained were used as starting materials for the synthesis of isomeric triazolopyrimidines as well as tetrazolopyrimidines. Furthermore, the rearrangement of triazolopyrimidines 7 into triazolopyrimidines 8 is also presented. In DMSO tetrazolopyrimidines 10 were shown to be in equilibrium with the relevant azidopyrimidines 9. The tetrazolopyrimidine structure was confirmed by X-ray crystallography. The synthesized compounds were tested for their antimicrobial activity.

New Methods for the Synthesis of 3-Amino-6,7-Dihydro-5H-Cyclopenta[c]Pyridine-4-Carbonitriles and Cyclopenta[d]Pyrazolo[3,4-b]Pyridines via a Smiles-type Rearrangement

By reaction with sodium ethoxide and as a function of their structures, 2-[(1-alkyl(aryl)-4-cyano-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yl)oxy]acetamides 11 gave 1-amino-5-alkyl(aryl)-7,8-dihydro-6H-cyclopenta[d]furo[2,3-b]pyridine-2-carboxamides 10 and/or 1-alkyl(aryl)-3-amino-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitriles 12.