126978-95-8Relevant articles and documents
A novel synthesis of imidazo[2,1-d][1,2,4]triazine and imidazo[2,1- dl]1,2,5]triazepine derivatives via ketene-N,N-acetal
El-Saghier, Ahmed M. M.,Maihub, Abdussalam A.,Al-Shirayda, Hatif A.
, p. 2433 - 2444 (1997)
The ketene-S,S-acetal I was prepared under phase-transfer catalysis (PTC) in benzene-carbonate two phase system using tetrabutylammonium bromide as the catalyst. Upon treatment with 1,2-diaminoethane, followed by hydrolysis with sodium methoxide, I gave 2-(2-oxopropylidene) imidazoline III. Bromination of III and replacement of bromine by hydrazine afforded 2- (1-hydazino-1,2-oxopropylidene) imidazoline V. Compound V was used as a precursor for the preparation of the previously unreported fused nitrogen heterocyclic ring system of imidazotriazine VI, VIII, XI, XII and imidazotriazepine IX, X.
Synthesis of Acetyl-Substituted Heterocyclic Ketene Aminals and Their Deactylation Reaction
Wang, He-Ting,Wang, Xiao-Jun,Huang, Zhi-Tang
, p. 2141 - 2145 (2007/10/02)
The acetyl-substituted heterocyclic ketene aminals 3-6 were synthesized by the reaction of ketene dithioacetals 2 with diamines.The deacetylation of heterocyclic diacetyl ketene-aminals by alkali was studied, and the corresponding monoacetyl derivatives were studied.
