127053-27-4

Basic information

• Product Name: (+)-(4aR,8aS)-3,4,4a,5,8,8a-Hexahydro-4a-hydroxy-8a-phenylthio-1,6(2H,7H)-naphthalenedione
• Synonyms: (+)-(4aR,8aS)-3,4,4a,5,8,8a-Hexahydro-4a-hydroxy-8a-phenylthio-1,6(2H,7H)-naphthalenedione
• CAS NO: 127053-27-4
• Molecular Weight: 290.383
• Mol File: 127053-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-(4aR,8aS)-3,4,4a,5,8,8a-Hexahydro-4a-hydroxy-8a-phenylthio-1,6(2H,7H)-naphthalenedione(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(4aR,8aS)-3,4,4a,5,8,8a-Hexahydro-4a-hydroxy-8a-phenylthio-1,6(2H,7H)-naphthalenedione(127053-27-4)
• EPA Substance Registry System: (+)-(4aR,8aS)-3,4,4a,5,8,8a-Hexahydro-4a-hydroxy-8a-phenylthio-1,6(2H,7H)-naphthalenedione(127053-27-4)

Safety Data

• Hazardous Substances Data: 127053-27-4(Hazardous Substances Data)

Upstream product

• 14204-24-1 N-(phenylthio)succinimide 
• 504-02-9 1,3-cylohexanedione 
• 72302-56-8 2-Phenylthio-1,3-cyclohexanedione 
• 127053-25-2 2-(3-Oxobutyl)-2-phenylthio-1,3-cyclohexanedione 

Downstream Products

• 127053-29-6 (+)-(8aS)-3,4,8,8a-Tetrahydro-8a-phenylthio-1,6(2H,7H)-naphthalenedione 

Relevant articles and documents

Enantioselective Synthesis of (-)-(7aS)-2,3,7,7a-Tetrahydro-7a-phenylthio-1H-indene-1,5(6H)-dione and (+)-(8aS)-3,4,8,8a-Tetrahydro-8a-phenylthio-1,6(2H,7H)-naphthalenedione

Application of the Hajos-Parrish asymmetrically biased aldol condensation to 2-(3-oxobutyl)-2-phenylthio-1,3-cyclopentanedione (5a) or 2-(3-oxobutyl)-2-phenylthio-1,3-cyclohexanedione (5b) using (R)-(+)-proline provided (-)-(7aS)-2,3,7,7a-tetrahydro-7a-phenylthio-1H-indene-1,5(6H)-dione (7a) and (+)-(8aS)-3,4,8,8a-tetrahydro-8a-phenylthio-1,6(2H,7H)-naphthalenedione (7b), respectively, in >/= 95percent enantiomeric excess, as determined by 1H-NMR analysis using triseuropium(III).