1270915-86-0Relevant articles and documents
Synthesis and biological evaluation of gemfibrozil chiral analogues as potential PPARα agonists
De Filippis, Barbara,Giampietro, Letizia,Giancristofaro, Antonella,Ammazzalorso, Alessandra,Fantacuzzi, Marialuigia,Maccallini, Cristina,Petruzzelli, Michele,Amoroso, Rosa
experimental part, p. 154 - 158 (2012/02/04)
Two series of gemfibrozil chiral analogues were synthesized and evaluated for their agonistic activity on PPARα receptor, belonging to the transcription factor family. A simple method to synthesize ureidic and thioureidic fibrates is described. Their abil