127143-28-6

Basic information

• Product Name: Benzene, 1-(2-chloro-2-nitroethenyl)-4-methoxy-, (Z)-
• CAS NO: 127143-28-6
• Molecular Formula: C9H8ClNO3
• Molecular Weight: 213.62
• Mol File: 127143-28-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2-chloro-2-nitroethenyl)-4-methoxy-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2-chloro-2-nitroethenyl)-4-methoxy-, (Z)-(127143-28-6)
• EPA Substance Registry System: Benzene, 1-(2-chloro-2-nitroethenyl)-4-methoxy-, (Z)-(127143-28-6)

Safety Data

• Hazardous Substances Data: 127143-28-6(Hazardous Substances Data)

Upstream product

• 1794-84-9 monochloronitromethane 
• 123-11-5 4-methoxy-benzaldehyde 
• 3910-55-2 N-(p-methoxybenzylidene)butylamine 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 
• 563-70-2 bromonitromethane 

Downstream Products

• 1093386-30-1 ethyl (-)-{[(2R)-3-{[5-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]oxy}-2-methylpropyl]oxy}-acetate 
• 1092938-25-4 tert-butyl (6R)-6-[(5-cyclohex-1-en-1-yl-6-phenylfuro[2,3-d]pyrimidin-4-yl)oxy]heptanoate 
• 1092938-21-0 C₂₉H₃₆N₂O₅ 

Relevant articles and documents

Chlorination of Conjugated Nitroalkenes with PhICl 2and so 2Cl 2for the Synthesis of α-Chloronitroalkenes

Chlorination of conjugated nitroalkenes with iodobenzene dichloride or sulfuryl chloride to give target α-chloronitroalkenes in good yields is described. Details of the procedure depend on the donating ability of the nitroalkene substituents. The activity of the described chlorinating agents increases in order 'PhICl 2/Py' 2Cl 2' 2Cl 2/HCl' with the former producing the best yields for highly donating substrates and the latter for non-activated groups. An autocatalytic role of hydrogen chloride and the chemoselectivity of chlorination were also demonstrated.

Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof

The present application relates to novel, acyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.

A Convenient Synthesis of 3-Chloro-3,4-dihydro-4-hydroxy-3-nitro-2-phenyl-2H-1-benzopyrans

The novel title compounds 5 are prepared by a simple and efficient two-step procedure starting from substituted benzaldehydes 1.A convenient route to the (2-chloro-2-nitroethenyl)benzenes 3 required as intermediates in the synthesis is reported.