127168-91-6

Basic information

• Product Name: Methyl 2,3-bis(broMoMethyl)benzoate
• Synonyms: Methyl 2,3-bis(broMoMethyl)benzoate
• CAS NO: 127168-91-6
• Molecular Formula: C₁₀H₁₀Br₂O₂
• Molecular Weight: 321.9932
• Mol File: 127168-91-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 375.4 °C at 760 mmHg
• Flash Point: 180.8 °C
• Appearance: /
• Density: 1.728 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Methyl 2,3-bis(broMoMethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2,3-bis(broMoMethyl)benzoate(127168-91-6)
• EPA Substance Registry System: Methyl 2,3-bis(broMoMethyl)benzoate(127168-91-6)

Safety Data

• Hazardous Substances Data: 127168-91-6(Hazardous Substances Data)

Usage

General Description

Methyl 2,3-bis(bromomethyl)benzoate is a chemical compound with the molecular formula C10H11Br2O2. It is a white solid substance that is often used as a reagent in chemical synthesis and research. Methyl 2,3-bis(broMoMethyl)benzoate is a brominated ester, meaning it contains bromine atoms attached to the benzene ring. It is commonly used in organic chemistry as a building block for the synthesis of various pharmaceuticals, agrochemicals, and materials. Its unique structure and reactivity make it a useful tool for creating complex organic molecules in the lab. Overall, methyl 2,3-bis(bromomethyl)benzoate is a versatile and important chemical compound in the field of organic synthesis.

Upstream product

• 15012-36-9 methyl 2,3-dimethylbenzoate 
• 186581-53-3 diazomethane 
• 214619-64-4 2,3-Bis-bromomethyl-benzoic acid 
• 603-79-2 2,3-dimethylbenzoic acid 
• 56-23-5 tetrachloromethane 

Downstream Products

• 214619-65-5 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid methyl ester 
• 214619-66-6 2,3-Bis-(diethoxy-phosphorylmethyl)-benzoic acid 
• 2211-83-8 4-methyl-3H-isobenzofuran-1-one 
• 72288-75-6 3-hydroxy-4-methylisobenzofuran-1(3H)-one 
• 127168-92-7 methyl 2-benzylisoindoline-4-carboxylate 
• 533889-80-4 C₂₂H₁₈Cl₂O₄ 

Relevant articles and documents

2-CYANOISOINDOLINE DERIVATIVES FOR TREATING CANCER

The invention relates to novel compounds of formula I which are inhibitors of deubiquitylating enzymes (DUBs) and/or desumoylating enzymes. In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 7 or ubiquitin specific peptidase 7 (USP7). The invention further relates to methods for the preparation of these compounds and to their use in the treatment of cancer.

AMIDE RESORCINOL COMPOUNDS

The present invention is directed to amide resorcinol compounds and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as HSP-90 inhibitors.

Synthesis of Substrate Analogues and Inhibitors for the Phosphoglycerate Mutase Enzyme

Several substrate analogues of the title enzyme were synthesized as well as with possible irreversible inhibitors, analogues of phosphoglycolate, the cofactor for this enzyme.The main routes involved an Arbuzov type reaction on functionalized halides, a reaction significantly improved by a sonication procedure and reaction of the diethylphosphite anion on tosylates.Phosphorylated epoxides were obtained by quantitative oxidation of conjugate double bonds using DMDO.Preliminary assays indicated a promising activity in some of these compounds.Keywords: phosphonates; inhibitors; phosphoglycerate Mutase; Arbuzov; DMDO