1271809-52-9

Basic information

• Product Name: 4-(3-(3-nitrophenyl)piperazin-1-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
• Synonyms: 4-(3-(3-nitrophenyl)piperazin-1-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
• CAS NO: 1271809-52-9
• Molecular Weight: 478.531
• Mol File: 1271809-52-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-(3-nitrophenyl)piperazin-1-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-(3-nitrophenyl)piperazin-1-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine(1271809-52-9)
• EPA Substance Registry System: 4-(3-(3-nitrophenyl)piperazin-1-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine(1271809-52-9)

Safety Data

• Hazardous Substances Data: 1271809-52-9(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 479633-63-1 4-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine 
• 65709-29-7 2-(3-nitrophenyl)-piperazine 

Downstream Products

• 1271809-56-3 3-(1-(2-((tert-butyldimethylsilyl)oxy)ethyl)-4-(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl)aniline 

Relevant articles and documents

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Since the approval of ibrutinib for the treatment of B-cell malignancies in 2012, numerous clinical trials have been reported using covalent inhibitors to target Bruton's tyrosine kinase (BTK) for oncology indications. However, a formidable challenge for