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1271948-76-5

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1271948-76-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1271948-76-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,1,9,4 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1271948-76:
(9*1)+(8*2)+(7*7)+(6*1)+(5*9)+(4*4)+(3*8)+(2*7)+(1*6)=185
185 % 10 = 5
So 1271948-76-5 is a valid CAS Registry Number.

1271948-76-5Downstream Products

1271948-76-5Relevant articles and documents

Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2

Fujimoto, Kazuki,Matsuoka, Eriko,Asada, Naoya,Tadano, Genta,Yamamoto, Takahiko,Nakahara, Kenji,Fuchino, Kouki,Ito, Hisanori,Kanegawa, Naoki,Moechars, Diederik,Gijsen, Harrie J. M.,Kusakabe, Ken-Ichi

, p. 5080 - 5095 (2019/05/28)

BACE1 inhibitors hold potential as agents in disease-modifying treatment for Alzheimer's disease. BACE2 cleaves the melanocyte protein PMEL in pigment cells of the skin and eye, generating melanin pigments. This role of BACE2 implies that nonselective and

2 -AMINODIHYDRO [1, 3] THIAZINES AS BACE 2 INHIBITORS FOR THE TREATMENT OF DIABETES

-

, (2011/04/18)

This invention relates to the use of aminodihydrothiazines of the formula wherein R1 to R3 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof, and pharmaceutical compositions con

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